D-Dimer
Latex enhanced immuno turbidimetric assay
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Product description:
D-dimer is the plasmin derived Fibrinolysis-specific Degradation Product (FDP) found in the
circulation. It contains two D-fragments of cross linked fibrin. D-dimer is very sensitive to
intravascular thrombus and may be markedly elevated in Disseminated Intravascular Coagulation
(DIC), acute aortic dissection, and Pulmonary Embolism (PE). Plasma levels of D-dimer can also
be increased in a variety of other conditions including malignancy, inflammatory conditions, and
infections making it not suitable to be a marker. However, because of its exquisite sensitivity,
the negative tests are useful in the exclusion of venous thromboembolism (VTE), a life
threatening disorder that includes DVT and PE.
The diagnosis of VTE and DIC are difficult, time-consuming, and expensive process. Generally the
assays for the detection of FDPs and D-dimer are used in many laboratories to investigate these
disorders. The Q-line D-dimer Platinum assay use liquid-phase latex enhanced agglutination
technology for automated biochemistry analyzers.
